Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303903 | 0.84 | S1PR1 (0.41) | S1PR1S1PR2S1PR4S1PR3PPARA | |
| SCHEMBL8972535 | 0.79 | DYRK1A (0.45) | ALDH1A1PKMKDM4E | |
| SCHEMBL10597811 | 0.79 | PKM (0.44) | ALDH1A1PKM | |
| SCHEMBL10889976 | 0.78 | PKM (0.44) | ALDH1A1PKMKDM4E | |
| SCHEMBL8972422 | 0.78 | RAB9A (0.47) | ALDH1A1PKMKDM4E | |
| SCHEMBL9307086 | 0.77 | S1PR1 (0.44) | S1PR1S1PR2S1PR4S1PR3PPARA | |
| SCHEMBL9443217 | 0.77 | HPGD (0.45) | ALDH1A1 | |
| SCHEMBL9443100 | 0.77 | GPR35 (0.35) | S1PR1S1PR2S1PR4S1PR3OXER1 | |
| SCHEMBL8972967 | 0.77 | NPC1 (0.52) | ALDH1A1PKMKDM4E | |
| SCHEMBL8973369 | 0.77 | HDAC6 (0.55) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0375614-B1 | CORROSION-INHIBITING COATING COMPOSITIONS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5198482-A | Benzothiazole carboxylic acid amine salt | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0375614-A1 | Corrosion-inhibiting coating compositions | CIBA-GEIGY AG (CH) | 1990-06-27 | — | — | EP | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |