Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GOT1 | P17174 | 2/20 | 0.65 |
| ▸ | AANAT | Q16613 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839075 | 0.89 | MEN1 (0.65) | MEN1KMT2AGOT1AANATGFER | |
| SCHEMBL9302255 | 0.88 | GFER (0.70) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL9117842 | 0.87 | MEN1 (0.76) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL7677886 | 0.84 | MEN1 (0.84) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL9304042 | 0.84 | KMT2A (0.67) | MEN1KMT2AGFERMTNR1A | |
| SCHEMBL7852138 | 0.82 | GFER (0.69) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL7852879 | 0.82 | GFER (0.84) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL12009643 | 0.81 | GFER (0.91) | MEN1KMT2AAANATGFERMTNR1A | |
| SCHEMBL1520606 | 0.81 | IDO1 (0.61) | MEN1KMT2AGOT1AANATMMP9 | |
| SCHEMBL4536522 | 0.81 | AANAT (0.80) | MEN1KMT2AAANATGFERMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283343-A | Melatonin antagonists | WHITBY RESEARCH, INC. (US) | 1994-02-01 | — | — | US | disclosed |
| US-5093352-A | Melatonin inhibitor, sleep, 2-aryl N-acetyl tryptamine | WHITBY RESEARCH, INC. (US) | 1992-03-03 | — | — | US | disclosed |