Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPPA | P01160 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304407 | 1.00 | HRH3 (0.36) | HRH3PTPN1P2RY2HCAR3HCAR2 | |
| SCHEMBL15592323 | 0.86 | NPPA (0.38) | HRH3PTPN1P2RY2CES1ALOX5AP | |
| SCHEMBL1760523 | 0.77 | HCAR2 (0.39) | HRH3PTPN1P2RY2HCAR2CES1 | |
| SCHEMBL3590995 | 0.77 | CES1 (0.38) | HRH3PTPN1P2RY2CES1ALOX5AP | |
| SCHEMBL29224344 | 0.77 | PTPN1 (0.35) | HRH3PTPN1P2RY2CES1ALOX5AP | |
| SCHEMBL3436268 | 0.75 | SLC6A2 (0.39) | HRH3PTPN1P2RY2HCAR2CES1 | |
| SCHEMBL742811 | 0.74 | CES1 (0.39) | HRH3PTPN1P2RY2HCAR2CES1 | |
| SCHEMBL25387512 | 0.74 | HDAC1 (0.40) | HRH3PTPN1HCAR3HCAR2CES1 | |
| SCHEMBL18782175 | 0.74 | HCAR2 (0.42) | P2RY2HCAR3HCAR2CES1MME | |
| SCHEMBL13685198 | 0.73 | IGFBP3 (0.39) | PTPN1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321036-A | Treatment of diabetes, obesity and gastrointestinal disorders | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-14 | — | — | US | disclosed |