SCHEMBL9304483

SCHEMBL9304483

O=C(O)c1cc(OCCS(=O)(=O)c2ccc(-c3ccccc3)cc2)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.52
ACMSD Q8TDX5 4/20 0.51
DHFR P00374 1/20 0.51
HNF4A P41235 1/20 0.51
BCL2L1 Q07817 1/20 0.47
STAT3 P40763 3/20 0.43
MMP2 P08253 1/20 0.43
MMP7 P09237 1/20 0.43
MMP14 P50281 1/20 0.43
PTPN1 P18031 1/20 0.43
BCL2A1 Q16548 1/20 0.43
FFAR1 O14842 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192260 0.92 MCL1 (0.49) MCL1ACMSDDHFRHNF4ABCL2L1
SCHEMBL9190438 0.91 MCL1 (0.50) MCL1ACMSDDHFRHNF4ABCL2L1
SCHEMBL9189464 0.90 HNF4A (0.51) MCL1ACMSDHNF4ABCL2L1MMP2
SCHEMBL9189770 0.90 MMP1 (0.50) MCL1BCL2L1MMP2MMP14BCL2A1
SCHEMBL9186805 0.89 ALDH1A1 (0.46) MCL1BCL2A1KDM4EALDH1A1HPGD
SCHEMBL9190023 0.88 POLB (0.46) MCL1BCL2A1KDM4EALDH1A1HPGD
SCHEMBL9188725 0.88 HNF4A (0.56) MCL1ACMSDHNF4ABCL2L1STAT3
SCHEMBL9187227 0.87 MCL1 (0.61) MCL1MMP2MMP14BCL2A1FFAR1
SCHEMBL9186829 0.87 MCL1 (0.56) MCL1HNF4ABCL2L1BCL2A1FFAR1
SCHEMBL9189588 0.87 ALDH1A1 (0.54) MCL1ACMSDBCL2L1BCL2A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed
US-5094999-A Salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1992-03-10 US disclosed