SCHEMBL9304577

SCHEMBL9304577

CC(O)C(=O)OC(=O)CCl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951592 0.81 FAAH (0.30) FAAH
SCHEMBL15741318 0.80 MGAM (0.42) TP53ALDH1A1TSHRMEN1KMT2A
SCHEMBL935214 0.80 ALDH1A1 (0.42) TP53ALDH1A1TSHRMEN1KMT2A
SCHEMBL288874 0.80 NAAA (0.38) TP53ALDH1A1KMT2AMAPT
SCHEMBL11470104 0.80 HTT (0.36) TSHR
SCHEMBL17601570 0.79 GRIN2D (0.35)
SCHEMBL8157902 0.78 ALDH1A1 (0.40) TP53ALDH1A1TSHRMEN1KMT2A
SCHEMBL1591709 0.78 TDP1 (0.36) TP53TSHRMEN1KMT2AMAPT
SCHEMBL4366413 0.78 ALDH1A1 (0.40) TP53ALDH1A1TSHRMEN1KMT2A
SCHEMBL3253032 0.76 TP53 (0.33) TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4001190-A None JP disclosed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN disclosed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN disclosed
CN-115650948-A Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-01-31 CN disclosed
US-5326887-A Reacting ester of alpha hydroxy acid oligomer over fixed bed catalyst E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-05 US disclosed
JP-H041190-A PRODUCTION OF 3-METHYL-1,4-DIOXANE-2,5-DIONE RES INST FOR PROD DEV 1992-01-06 JP disclosed
US-4033938-A BIOLOGICALLY DEGRADABLE, SURGICAL USES AMERICAN CYANAMID COMPANY (US) 1977-07-05 US disclosed
US-3960152-A Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5-diones AMERICAN CYANAMID COMPANY (US) 1976-06-01 US disclosed