Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892695 | 0.92 | PARP10 (0.64) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL28620841 | 0.90 | PARP10 (0.62) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL29484786 | 0.88 | PARP10 (0.59) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL4260982 | 0.83 | LMNA (0.64) | PARP10SMN1; SMN2ALDH1A1TSHRPOLB | |
| SCHEMBL27863223 | 0.82 | LMNA (0.48) | PARP10SRD5A2ALDH1A1TSHRPOLB | |
| SCHEMBL16174814 | 0.82 | SMN1; SMN2 (0.55) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9240757 | 0.82 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL8209000 | 0.82 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL70401 | 0.82 | PARP10 (0.67) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 | |
| Diphenylether SCHEMBL9846088 | 0.81 | LTA4H (0.60) | PARP10SRD5A2SMN1; SMN2ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007107423-A1 | NEGATIVE WORKING, HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2007-09-27 | — | — | WO | disclosed |