Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ADH7 | P40394 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | DNM2 | P50570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305153 | 0.71 | ALDH1A1 (0.41) | ELANEGPR84ADH1BADH1CADH1A | |
| SCHEMBL2903201 | 0.71 | MAPT (0.43) | ELANEGPR84 | |
| SCHEMBL21367256 | 0.66 | ALDH1A1 (0.47) | ELANEGPR84ADRA2AADH1BADH1C | |
| SCHEMBL7528975 | 0.66 | EPHX1 (0.39) | GPR84ADRA2AADH1BADH1CADH1A | |
| SCHEMBL18386484 | 0.65 | CHRM2 (0.43) | ELANEGPR84EPHX1 | |
| SCHEMBL8979424 | 0.65 | ABL1 (0.49) | GPR84ADRA2AADH1BADH1CADH1A | |
| SCHEMBL424398 | 0.64 | HDAC3 (0.48) | ELANE | |
| SCHEMBL5543098 | 0.61 | ABL1 (0.45) | ADRA2AADH1BADH1CADH1AADH7 | |
| SCHEMBL3400985 | 0.61 | ADRA2A (0.53) | GPR84ADRA2AEPHX1DNM2 | |
| SCHEMBL24237033 | 0.60 | ADRA2A (0.49) | ELANEGPR84ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344974-A | Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid | SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) | 1994-09-06 | — | — | US | claimed |