Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305093 | 0.82 | MAPT (0.42) | ALDH1A1AKR1C3AKR1C2KMT2APOLB | |
| SCHEMBL9306813 | 0.81 | POLB (0.41) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL8972457 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL10888973 | 0.81 | POLB (0.40) | ALDH1A1KMT2APOLBMEN1KDM4E | |
| SCHEMBL9305523 | 0.81 | LMNA (0.43) | ALDH1A1KMT2AMEN1LMNAHSD17B10 | |
| SCHEMBL11119676 | 0.80 | HTT (0.50) | ALDH1A1HTTKMT2APOLBGRK6 | |
| SCHEMBL9305817 | 0.80 | MAPT (0.47) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL9734571 | 0.79 | RAB9A (0.34) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL8972641 | 0.79 | PPARA (0.48) | ALDH1A1HTTAKR1C3AKR1C2KMT2A | |
| SCHEMBL9305788 | 0.78 | HSD17B10 (0.39) | ALDH1A1KMT2APOLBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |