Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28172475 | 0.82 | KDM4E (0.35) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL8170906 | 0.80 | TAS1R3 (0.46) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL10222344 | 0.80 | GAA (0.53) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL253529 | 0.79 | PIK3CG (0.56) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL9305682 | 0.79 | RAB9A (0.46) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL21231323 | 0.76 | LMNA (0.41) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL20884011 | 0.76 | MAPT (0.39) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL12318134 | 0.76 | MAPT (0.61) | RAB9AMAPTNPC1TP53POLB | |
| SCHEMBL10271390 | 0.76 | NPC1 (0.64) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL2538594 | 0.76 | KDM4E (0.59) | RAB9ASMN1; SMN2MAPTNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |