Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304349 | 0.79 | — | — | |
| SCHEMBL15612602 | 0.76 | IDO1 (0.36) | IDO1GABRA1GABRB2 | |
| SCHEMBL2141988 | 0.75 | IDO1 (0.34) | IDO1PSMD14COPS5 | |
| SCHEMBL29719052 | 0.75 | IDO1 (0.34) | IDO1PSMD14COPS5 | |
| SCHEMBL27684067 | 0.73 | IDO1 (0.34) | IDO1GABRA1GABRB2 | |
| SCHEMBL9306237 | 0.73 | ALDH1A1 (0.36) | IDO1 | |
| SCHEMBL15531969 | 0.72 | — | — | |
| SCHEMBL6900847 | 0.69 | — | — | |
| SCHEMBL1951804 | 0.67 | — | — | |
| SCHEMBL18796087 | 0.65 | MAPT (0.32) | IDO1PSMD14COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359065-A | Reacting a bromo aromatic compound with an excess of silylating agent; forming metallized intermediate; quenching | EASTMAN KODAK COMPANY (US) | 1994-10-25 | — | — | US | disclosed |