Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18604569 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL15612602 | 0.76 | IDO1 (0.36) | ALDH1A1IDO1 | |
| SCHEMBL78717 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL9860862 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL28583070 | 0.74 | TRPA1 (0.52) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL70357 | 0.74 | — | — | |
| SCHEMBL29065923 | 0.73 | IDO1 (0.46) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL5090209 | 0.73 | IDO1 (0.34) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL9304969 | 0.73 | IDO1 (0.34) | IDO1 | |
| SCHEMBL1092768 | 0.72 | ERN1 (0.41) | ALDH1A1CA2TDP1CA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359065-A | Reacting a bromo aromatic compound with an excess of silylating agent; forming metallized intermediate; quenching | EASTMAN KODAK COMPANY (US) | 1994-10-25 | — | — | US | disclosed |