Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303002 | 0.82 | HCAR2 (0.34) | GPR84TLR8HCAR2HIF1AEPAS1 | |
| SCHEMBL2578095 | 0.70 | HIF1A (0.40) | GPR84HIF1AEPAS1MEN1MAPT | |
| SCHEMBL9534596 | 0.69 | HIF1A (0.42) | GPR84HIF1AEPAS1MEN1MAPT | |
| SCHEMBL28428038 | 0.68 | HIF1A (0.44) | GPR84HIF1AEPAS1MEN1MAPT | |
| SCHEMBL7088782 | 0.68 | HIF1A (0.44) | GPR84HIF1AEPAS1MEN1MAPT | |
| SCHEMBL28429565 | 0.68 | HIF1A (0.44) | GPR84HIF1AEPAS1MEN1MAPT | |
| SCHEMBL2742443 | 0.67 | GPR84 (0.40) | GPR84TLR8HIF1AEPAS1MEN1 | |
| SCHEMBL2802740 | 0.67 | MAPT (0.45) | GPR84TLR8SRCMAPTALOX15 | |
| SCHEMBL11114074 | 0.66 | TLR8 (0.46) | GPR84TLR8MEN1MAPTHTT | |
| SCHEMBL9789122 | 0.66 | GPR84 (0.39) | GPR84TLR8HIF1AEPAS1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344974-A | Process for the preparation of N-acyl derivatives of 5-aminolevulinic acid, as well as the hydrochloride of the free acid | SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHENSFURT (DE) | 1994-09-06 | — | — | US | claimed |
| EP-0584585-A1 | Process for the preparation of N-acylderivatives of the acid 5-aminolevulinic and their hydrochlorides | SÜDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT (DE) | 1994-03-02 | — | — | EP | claimed |