Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8137163 | 0.87 | KDM4E (0.39) | NAMPTKDM4CCYP2D6KDM4ETSHR | |
| SCHEMBL9305230 | 0.84 | MAOA (0.36) | MAOAMAOBACHEBUB1KDM4C | |
| SCHEMBL9303643 | 0.83 | CYP2D6 (0.45) | MAOAMAOBACHEBUB1CYP2D6 | |
| Hydrochloric Acid SCHEMBL8138778 | 0.83 | TDP1 (0.36) | MAOAMAOBACHEBUB1NAMPT | |
| SCHEMBL9302920 | 0.82 | TDP1 (0.41) | MAOAMAOBACHECYP2D6KDM4E | |
| SCHEMBL8138731 | 0.81 | NAMPT (0.39) | NAMPTCYP2D6TAAR1CARM1PRMT6 | |
| SCHEMBL9304696 | 0.81 | CYP2D6 (0.52) | KDM4CCYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL8134106 | 0.81 | CYP2D6 (0.44) | MAOAMAOBACHEBUB1KDM4C | |
| Hydrochloric Acid SCHEMBL8142483 | 0.81 | TDP1 (0.42) | MAOAMAOBACHECYP2D6KDM4E | |
| Hydrochloric Acid SCHEMBL8137559 | 0.80 | CYP2D6 (0.50) | KDM4CCYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |