Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8138778 | 0.99 | TDP1 (0.36) | MAOAMAOBACHETDP1KDM4E | |
| SCHEMBL9302920 | 0.93 | TDP1 (0.41) | MAOAMAOBACHETDP1KDM4E | |
| Hydrochloric Acid SCHEMBL8142483 | 0.91 | TDP1 (0.42) | MAOAMAOBACHETDP1KDM4E | |
| SCHEMBL9305072 | 0.86 | CSNK2A2 (0.40) | MAOAMAOBACHETDP1 | |
| SCHEMBL8134219 | 0.85 | CDC7 (0.41) | MAOAMAOBACHETDP1 | |
| SCHEMBL8138791 | 0.85 | CSNK2A2 (0.39) | MAOAMAOBACHETDP1CYP2D6 | |
| SCHEMBL9305300 | 0.84 | MAOA (0.34) | MAOAMAOBACHEKDM4ETSHR | |
| SCHEMBL9303643 | 0.84 | CYP2D6 (0.45) | MAOAMAOBACHETDP1CYP2D6 | |
| SCHEMBL9306122 | 0.82 | HSD17B10 (0.47) | MAOAMAOBACHEKDM4ETSHR | |
| SCHEMBL9304696 | 0.82 | CYP2D6 (0.52) | TDP1KDM4ECYP2D6NPC1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |