Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 3/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8142483 | 0.99 | TDP1 (0.42) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9305230 | 0.93 | MAOA (0.36) | TDP1CAMK2DMAOAMAOBACHE | |
| Hydrochloric Acid SCHEMBL8138778 | 0.91 | TDP1 (0.36) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9305829 | 0.86 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9304149 | 0.85 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9304250 | 0.85 | TDP1 (0.41) | TDP1CAMK2DMAOAMAOBACHE | |
| SCHEMBL9304696 | 0.85 | CYP2D6 (0.52) | TDP1KDM4ERPS6KA5CYP2D6 | |
| Hydrochloric Acid SCHEMBL8137559 | 0.83 | CYP2D6 (0.50) | TDP1KDM4ERPS6KA5CYP2D6 | |
| Hydrochloric Acid SCHEMBL8137553 | 0.83 | CYP2D6 (0.50) | TDP1KDM4ERPS6KA5CYP2D6 | |
| SCHEMBL9303821 | 0.82 | PRKCB (0.40) | TDP1CAMK2DMERTKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | claimed |