SCHEMBL9305467

SCHEMBL9305467

O=C(O)c1ccc(Oc2cccc(S(=O)(=O)c3ccccc3)c2)cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.56
POLB P06746 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
APEX1 P27695 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
BCL2L1 Q07817 1/20 0.48
XDH P47989 3/20 0.46
SLC22A12 Q96S37 3/20 0.46
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KAT6A Q92794 1/20 0.44
CA12 O43570 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304358 0.92 MCL1 (0.62) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL9304480 0.91 HTT (0.58) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL9304326 0.89 POLB (0.50) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL7631413 0.85 POLB (0.62) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL9304104 0.81 L3MBTL1 (0.58) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL9304667 0.81 HTT (0.59) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL9304588 0.80 POLB (0.56) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL14213143 0.80 ALDH1A1 (0.65) MCL1POLBXDHSLC22A12CYP2C9
SCHEMBL11008742 0.80 POLB (0.71) MCL1POLBL3MBTL1APEX1CTDSP1
SCHEMBL712913 0.79 POLB (0.48) MCL1POLBL3MBTL1APEX1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276001-A Color developer comprising salicylic acid derivative KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-01-04 US disclosed