Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304020 | 0.84 | KMT2A (0.57) | MEN1KMT2AMAPTPKMMTOR | |
| SCHEMBL9304024 | 0.84 | KMT2A (0.57) | MEN1KMT2AMAPTPKMMTOR | |
| SCHEMBL9304030 | 0.84 | KMT2A (0.57) | MEN1KMT2AMAPTPKMMTOR | |
| SCHEMBL9472042 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTTHRBPKM | |
| SCHEMBL9297101 | 0.80 | PKM (0.51) | MEN1KMT2AMAPTTHRBPKM | |
| SCHEMBL9471190 | 0.78 | KMT2A (0.55) | MEN1KMT2AMAPTTHRBPKM | |
| SCHEMBL9471117 | 0.78 | THRB (0.52) | MEN1KMT2AMAPTTHRBPKM | |
| SCHEMBL9472078 | 0.77 | MEN1 (0.53) | MEN1KMT2AMAPTTHRBPKM | |
| SCHEMBL9471097 | 0.77 | THRB (0.58) | MEN1KMT2ATHRBPKMALDH1A1 | |
| SCHEMBL9471112 | 0.75 | NPSR1 (0.53) | MEN1KMT2AMAPTTHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338760-A | Urea derivatives, their preparation and medicinal products containing them | RHONE-POULENC RORER S.A. (FR) | 1994-08-16 | — | — | US | disclosed |