Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGAV | P06756 | 2/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304020 | 1.00 | KMT2A (0.57) | KMT2AMEN1MAPTITGB3ITGAV | |
| SCHEMBL9304024 | 1.00 | KMT2A (0.57) | KMT2AMEN1MAPTITGB3ITGAV | |
| SCHEMBL9305569 | 0.84 | MEN1 (0.47) | KMT2AMEN1MAPTCYP26A1SAE1 | |
| SCHEMBL687648 | 0.83 | MEN1 (0.48) | KMT2AMEN1MAPTITGB3ITGAV | |
| SCHEMBL19195329 | 0.82 | KMT2A (0.60) | KMT2AMEN1MAPTSAE1UBA2 | |
| SCHEMBL20335082 | 0.80 | FPR2 (0.59) | KMT2AMEN1MAPTSAE1UBA2 | |
| SCHEMBL5408556 | 0.78 | UTS2R (0.57) | CYP26A1SMN1; SMN2CTSA | |
| SCHEMBL5409846 | 0.78 | ROCK2 (0.64) | KMT2AMEN1ITGB3HSD17B10CTSA | |
| Toluene SCHEMBL11581740 | 0.77 | KMT2A (0.65) | KMT2AMEN1MAPTSAE1UBA2 | |
| SCHEMBL20312093 | 0.77 | CYP26A1 (0.58) | ITGB3ITGAVCYP26A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338760-A | Urea derivatives, their preparation and medicinal products containing them | RHONE-POULENC RORER S.A. (FR) | 1994-08-16 | — | — | US | disclosed |