Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755644 | 0.90 | TYR (0.66) | TYRGABRA1GABRB2TSHRHPGD | |
| SCHEMBL29366137 | 0.90 | TYR (0.66) | TYRGABRA1GABRB2TSHRHPGD | |
| Phosphoric Acid SCHEMBL28355238 | 0.82 | SRC (0.56) | TYRACP3SRCALDH1A1ANPEP | |
| Phosphoric Acid SCHEMBL3772748 | 0.80 | GABRA1 (0.78) | TYRGABRA1GABRB2ACP3TSHR | |
| Phosphoric Acid SCHEMBL7921309 | 0.80 | GABRA1 (0.78) | TYRGABRA1GABRB2ACP3TSHR | |
| Phosphoric Acid SCHEMBL28546758 | 0.80 | SRC (0.54) | TYRACP3SRCALDH1A1ANPEP | |
| Phosphoric Acid SCHEMBL1078532 | 0.80 | TYR (0.50) | TYRACP3SRCHPGDKDM4E | |
| SCHEMBL30485781 | 0.79 | TYR (0.61) | TYRGABRA1GABRB2TSHRHPGD | |
| SCHEMBL922828 | 0.79 | TYR (0.61) | TYRGABRA1GABRB2TSHRHPGD | |
| Phenol SCHEMBL333075 | 0.78 | GABRA1 (0.67) | GABRA1GABRB2ACP3TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334585-A | Pyrethroid microemulsion compositions and method for controlling insects therewith | RHONE-POULENC CHIMIE (FR) | 1994-08-02 | — | — | US | disclosed |