Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244935 | 0.80 | TP53 (0.58) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL701861 | 0.79 | TAS1R3 (0.65) | TAS1R3TAS1R1 | |
| SCHEMBL24162929 | 0.78 | TP53 (0.66) | HPGDALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL13080228 | 0.75 | RAB9A (0.42) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL9734495 | 0.75 | SMN1; SMN2 (0.52) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL1101422 | 0.74 | MAPT (0.53) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL29364250 | 0.74 | MAPT (0.53) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8597623 | 0.74 | SMN1; SMN2 (0.57) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8653471 | 0.73 | NPC1 (0.46) | HPGDALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL28326194 | 0.72 | L3MBTL1 (0.73) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |