Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305796 | 0.89 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL8972661 | 0.84 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL8972432 | 0.79 | LMNA (0.45) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305589 | 0.79 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL10892262 | 0.79 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305087 | 0.79 | MAPT (0.46) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305516 | 0.79 | TLR4 (0.44) | RAB9ANPC1KMT2ATP53MAPT | |
| SCHEMBL8972447 | 0.78 | NPC1 (0.42) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9306804 | 0.78 | PIK3CG (0.44) | RAB9ASMN1; SMN2ALDH1A1MAPTHDAC4 | |
| SCHEMBL8972323 | 0.78 | NPC1 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |