Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305783 | 0.89 | RAB9A (0.34) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL8972672 | 0.85 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL8973151 | 0.80 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1KMT2AHPGD | |
| SCHEMBL8972448 | 0.80 | LMNA (0.48) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305602 | 0.80 | GAA (0.44) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL10892271 | 0.80 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305528 | 0.80 | RAB9A (0.44) | RAB9ANPC1KDM4EKMT2AMAPT | |
| SCHEMBL9305097 | 0.80 | MAPT (0.49) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL9305778 | 0.80 | RAB9A (0.38) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL8972467 | 0.79 | MAPT (0.40) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |