Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305822 | 0.92 | MAPT (0.48) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9305804 | 0.81 | MAPT (0.49) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8972447 | 0.79 | NPC1 (0.42) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9306804 | 0.79 | PIK3CG (0.44) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9304714 | 0.79 | HDAC4 (0.36) | MAPTALDH1A1LMNAPOLB | |
| SCHEMBL9305516 | 0.77 | TLR4 (0.44) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9305087 | 0.77 | MAPT (0.46) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL8972323 | 0.76 | NPC1 (0.42) | MAPTKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL9305783 | 0.76 | RAB9A (0.34) | MAPTKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10888964 | 0.76 | ALDH1A1 (0.42) | MAPTKMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |