Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879440 | 0.84 | HRH3 (0.42) | HRH3LTA4HKDM4E | |
| SCHEMBL7705109 | 0.82 | GNAO1 (0.59) | KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL11889486 | 0.81 | HRH3 (0.56) | HRH3TSHR | |
| SCHEMBL11179141 | 0.81 | HRH3 (0.52) | HRH3TSHR | |
| SCHEMBL5489927 | 0.81 | HRH3 (0.52) | HRH3TSHR | |
| SCHEMBL15408001 | 0.81 | HRH3 (0.58) | HRH3GNAI3GNAO1GNAI1 | |
| SCHEMBL15408002 | 0.81 | HRH3 (0.58) | HRH3GNAI3GNAO1GNAI1 | |
| SCHEMBL23682856 | 0.79 | HRH3 (0.75) | HRH3LTA4HKDM4EGNAI3GNAO1 | |
| SCHEMBL11210615 | 0.79 | HRH3 (0.75) | HRH3LTA4HKDM4EGNAI3GNAO1 | |
| SCHEMBL27096 | 0.79 | HRH3 (0.75) | HRH3LTA4HKDM4EGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348964-A | Anticholesterol agents or fungicides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-20 | — | — | US | disclosed |