Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303378 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4GPR35ALOX15L3MBTL1 | |
| SCHEMBL30458055 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1193334 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL838256 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4090172 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2565885 | 0.82 | ALDH1A1 (0.69) | ALDH1A1CYP3A4MAPTGPR35MEN1 | |
| SCHEMBL30606309 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL10930822 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTGPR35MEN1 | |
| SCHEMBL9069658 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL27667756 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP3A4MAPTGPR35MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107964008-A | The preparation method of AZD9291 intermediates and AZD9291 | 李梦雪 | 2018-04-27 | — | — | CN | claimed |
| CN-107964008-A | The preparation method of AZD9291 intermediates and AZD9291 | 李梦雪 | 2018-04-27 | — | — | CN | disclosed |
| US-5374639-A | Plant fungicides | CIBA-GEIGY CORPORATION (US) | 1994-12-20 | — | — | US | disclosed |
| WO-1994018173-A1 | BENZIMIDAZOLESULFONIC ACID DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-08-18 | — | — | WO | disclosed |
| EP-0549532-A1 | Benzotriazole-sulfonic acid derivatives and their use as microbicides | CIBA-GEIGY AG (CH) | 1993-06-30 | — | — | EP | disclosed |
| US-4575378-A | Substituted 4-amino-3-nitrophenols, processes for their preparation and hair-coloring agents containing these compounds | HANS SCHWARZKOPF GMBH (DE) | 1986-03-11 | — | — | US | disclosed |