SCHEMBL303378

SCHEMBL303378

Nc1cc(Cl)c([N+](=O)[O-])cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 1.00
CYP3A4 P08684 1/20 1.00
VCAM1 P19320 2/20 0.47
MAPK1 P28482 2/20 0.47
GAA P10253 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
THRB P10828 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
GPR35 Q9HC97 3/20 0.46
CXCR2 P25025 2/20 0.46
TSHR P16473 1/20 0.46
SNCA P37840 1/20 0.44
PDE7A Q13946 1/20 0.42
NSD2 O96028 1/20 0.42
PLCG1 P19174 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4699370 0.92 ALDH1A1 (0.86) ALDH1A1CYP3A4VCAM1MAPK1GAA
SCHEMBL11588501 0.90 ALDH1A1 (0.81) ALDH1A1CYP3A4VCAM1MAPK1GAA
SCHEMBL9305937 0.85 ALDH1A1 (0.73) ALDH1A1CYP3A4MAPK1L3MBTL1ALOX15
SCHEMBL30979260 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPK1GAAL3MBTL1
SCHEMBL1192850 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4VCAM1MAPK1ALOX15
SCHEMBL838256 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4VCAM1MAPK1L3MBTL1
SCHEMBL10942341 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPK1GAAL3MBTL1
SCHEMBL29596496 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4VCAM1MAPK1ALOX15
SCHEMBL68172 0.84 ALDH1A1 (0.71) ALDH1A1CYP3A4VCAM1MAPK1ALOX15
SCHEMBL1725673 0.82 ALDH1A1 (0.69) ALDH1A1CYP3A4VCAM1MAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 735 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111952549-B Carbon-coated lithium battery negative electrode material with yolk-eggshell structure and preparation method thereof 宝山钢铁股份有限公司 2021-08-17 CN claimed
CN-111952549-A Carbon-coated lithium battery negative electrode material with yolk-eggshell structure and preparation method thereof 宝山钢铁股份有限公司 2020-11-17 CN claimed
CN-110950764-A Method for synthesizing 2-amino-4-chloro-5 nitrophenol in microchannel reactor 沈阳感光化工研究院有限公司 2020-04-03 CN claimed
CN-105753730-A Method for preparing 2-amino-4-chloro-5-nitrophenol 宜兴市新宇化工有限公司 2016-07-13 CN claimed
CN-102295838-A Six-branched azosiloxane dye and synthesis method thereof 2011-12-28 CN claimed
US-20110224335-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME KIM SUNG-HEE 2011-09-15 US claimed
US-7935552-B2 Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO., LTD. (KR) 2011-05-03 US claimed
CN-101993632-A Ink composition DONGJIN SEMICHEM CO LTD 2011-03-30 CN claimed
CN-101735690-A Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO LTD 2010-06-16 CN claimed
US-20100120181-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2010-05-13 US claimed
EP-0356393-B1 Process for the preparation of metallisable monoazo dyes CIBA GEIGY AG (CH) 1995-01-25 EP claimed
US-5003051-A Diazotizing, Coupling An Amine Using A Ketone Promoter CIBA-GEIGY CORPORATION (US) 1991-03-26 US claimed
EP-0356393-A2 Process for the preparation of metallisable monoazo dyes CIBA-GEIGY AG (CH) 1990-02-28 EP claimed
JP-59069755-A None JP disclosed
JP-59059656-A None JP disclosed
EP-4737445-A1 NOVEL SATURATED HETEROCYCLE-SUBSTITUTED HETEROARYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF Korea Institute of Science and Technology (KR) 2026-05-06 EP disclosed
US-3972890-A ACID CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3970615-A Unsymmetrical mono-sulfo containing chromium complexes of azo dyes CIBA-GEIGY CORPORATION (US) 1976-07-20 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed