Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136217 | 0.95 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9136225 | 0.92 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18979685 | 0.91 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL283500 | 0.86 | THRB (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7090691 | 0.84 | TSHR (0.81) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL196351 | 0.83 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9150298 | 0.82 | ALDH1A1 (0.63) | TSHRALDH1A1HPGDATMDGKA | |
| Isopropyl Alcohol SCHEMBL9283045 | 0.82 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14893 | 0.82 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11583525 | 0.82 | TSHR (0.84) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332852-A | Forming silyloxy unsaturated compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0243120-B1 | TOUGH FLEXIBLE POLYMER BLENDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5003004-A | Star Polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0355224-A1 | 1,4 -O- metallation process and composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4785126-A | PROMOTERS, POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-15 | — | — | US | disclosed |