Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.85 |
| ▸ | RECQL | P46063 | 3/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | HPGD | P15428 | 2/20 | 0.85 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.85 |
| ▸ | CASP1 | P29466 | 1/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.85 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | GLB1 | P16278 | 1/20 | 0.55 |
| ▸ | CTRC | Q99895 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | GNG2 | P59768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023355 | 0.92 | THRB (1.00) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL29380916 | 0.92 | THRB (1.00) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL31648221 | 0.92 | THRB (1.00) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL111115 | 0.92 | THRB (1.00) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1435780 | 0.91 | THRB (0.98) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL185362 | 0.91 | THRB (0.98) | THRBRECQLTDP1ALDH1A1HPGD | |
| Bromide SCHEMBL22494505 | 0.90 | SMAD3 (0.75) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL14982853 | 0.86 | THRB (0.87) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL1275840 | 0.86 | SMAD3 (0.66) | THRBRECQLTDP1ALDH1A1HPGD | |
| SCHEMBL6454855 | 0.85 | SMAD3 (0.65) | THRBRECQLTDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200315976-A1 | Encapsulation Methods and Compositions | PRODO LABORATORIES INC (US) | 2020-10-08 | — | — | US | disclosed |
| WO-1994020850-A1 | pH-ZONE-REFINING COUNTERCURRENT CHROMATOGRAPHY | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-09-15 | — | — | WO | disclosed |
| US-5332504-A | Acidification and basification of liquids and centrifuging | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200315976-A1 | Encapsulation Methods and Compositions | EPCAM, ICAM1, CD63 | THRB 4776/4885RECQL 1088/4885TDP1 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.