SCHEMBL111115

SCHEMBL111115

O=C1OC2(c3cc(Br)c(O)c(Br)c3Oc3c2cc(Br)c(O)c3Br)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 1.00
RECQL P46063 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
ALDH1A1 P00352 3/20 1.00
HPGD P15428 2/20 1.00
BRCA1 P38398 2/20 1.00
HSD17B10 Q99714 2/20 1.00
CYP3A4 P08684 1/20 1.00
TSHR P16473 1/20 1.00
MAPK1 P28482 1/20 1.00
CASP1 P29466 1/20 1.00
HIF1A Q16665 1/20 1.00
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
BLM P54132 2/20 0.63
GLB1 P16278 1/20 0.63
CTRC Q99895 1/20 0.63
SMAD3 P84022 1/20 0.60
PRMT1 Q99873 1/20 0.57
PTPN11 Q06124 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023355 1.00 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29380916 1.00 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL31648221 1.00 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL185362 0.99 THRB (0.98) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL1435780 0.99 THRB (0.98) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL14982853 0.93 THRB (0.87) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL9305980 0.92 THRB (0.85) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29351543 0.84 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29024627 0.84 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29861375 0.84 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364115-A1 NOVEL PSYCHEDELIC COMPOSITIONS, DELIVERY SYSTEMS AND THERAPEUTIC USES THEREOF MYDECINE INNOVATIONS GROUP INC (US) 2023-11-16 US claimed
CN-116355437-A Preparation method for improving saturation of bromofluorescein lake 湖南金桥新材料科技有限公司 2023-06-30 CN claimed
US-20210220333-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING FILARIAL DISEASE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2021-07-22 US claimed
EP-3846817-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING FILARIAL DISEASE The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (US) 2021-07-14 EP claimed
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 EP claimed
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP claimed
EP-2108952-B1 Method for detection of a target compound based on a redox-reaction of a phenothiazine dye ARKRAY INC (JP) 2015-10-28 EP claimed
EP-2543706-A2 Stabilizer of color former and use thereof ARKRAY, Inc. (JP) 2013-01-09 EP claimed
US-8273577-B2 Method for detecting phenothiazine-derivative color and color-developer reagent used therein ARKRAY, INC. (JP) 2012-09-25 US claimed
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF ARKRAY, INC. (JP) 2011-01-20 US claimed
EP-2270105-A1 STABILIZER FOR COLOR DEVELOPER AND USE THEREOF ARKRAY, Inc. (JP) 2011-01-05 EP claimed
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, INC. (JP) 2010-05-06 US claimed
EP-2108952-A1 METHOD FOR DETECTION OF PHENOTHIAZINE DERIVATIVE DYE, AND COLOR-DEVELOPER REAGENT FOR USE IN THE METHOD Arkray, Inc. (JP) 2009-10-14 EP claimed
US-6966213-B2 Rapid method for detecting leaks of hydraulic fluids in production plants NALCO COMPANY (US) 2005-11-22 US claimed
US-20050160795-A1 Rapid method for detecting leaks of hydraulic fluids in production plants ECOLAB USA INC. 2005-07-28 US claimed
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants PROCTER & GAMBLE COMPANY, THE 2003-06-12 US claimed
EP-1235544-A1 TARTAR CONTROL DENTURE ADHESIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2002-09-04 EP claimed
WO-2001041710-A1 TARTAR CONTROL DENTURE ADHESIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-06-14 WO claimed
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL ICHOR MICROBIAL SOLUTIONS INC (US) 2026-03-12 US disclosed
US-5274086-A A xanthene derivative KIKKOMAN CORPORATION (JP) 1993-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068887-A1 XANTHENE DYE COMBINATIONS FOR ENHANCED BACTERIAL, YEAST, AND FUNGAL MICROBIAL CONTROL TYR, PPOX, TH THRB 2676/4885RECQL 297/4885TDP1 497/4885
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN TH, TYR, HPD THRB 1943/4885RECQL 3111/4885TDP1 2996/4885
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants TAS2R10, TAS1R1, TAS2R40 THRB 1948/4885RECQL 4231/4885TDP1 2193/4885
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF TYR, CRYZ, MITF THRB 4885/4885RECQL 389/4885TDP1 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.