SCHEMBL185362

SCHEMBL185362

O=C1OC2(c3cc(Br)c(O)c(Br)c3Oc3c2cc(Br)c(O)c3Br)c2c(Cl)c(Cl)c(Cl)c(Cl)c21.[NaH].[NaH]

nearest known ligand 0.98

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.98
RECQL P46063 3/20 0.98
TDP1 Q9NUW8 3/20 0.98
ALDH1A1 P00352 3/20 0.98
HPGD P15428 2/20 0.98
BRCA1 P38398 2/20 0.98
HSD17B10 Q99714 2/20 0.98
CYP3A4 P08684 1/20 0.98
TSHR P16473 1/20 0.98
MAPK1 P28482 1/20 0.98
CASP1 P29466 1/20 0.98
HIF1A Q16665 1/20 0.98
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
BLM P54132 2/20 0.62
GLB1 P16278 1/20 0.62
CTRC Q99895 1/20 0.62
SMAD3 P84022 1/20 0.59
PRMT1 Q99873 1/20 0.56
PTPN11 Q06124 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31648221 0.99 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29380916 0.99 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL30023355 0.99 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL111115 0.99 THRB (1.00) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL1435780 0.98 THRB (0.98) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL14982853 0.92 THRB (0.87) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL9305980 0.91 THRB (0.85) THRBRECQLTDP1ALDH1A1HPGD
Potassium Ion SCHEMBL30027234 0.83 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29861375 0.83 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD
SCHEMBL29351543 0.83 THRB (0.72) THRBRECQLTDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240125705-A1 ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY ESSENLIX CORPORATION (US) 2024-04-18 US disclosed
US-11906432-B2 Enhanced, rapid, homogeneous, cell staining and assay ESSENLIX CORPORATION (US) 2024-02-20 US disclosed
EP-3775875-B1 METHOD AND DEVICE FOR THE DETERMINATION OF FILM FORMING AMINES IN A LIQUID FRAMATOME GMBH (DE) 2023-11-29 EP disclosed
US-20230127982-A1 INDICATOR FILM INSIGNIA TECHNOLOGIES LTD (GB) 2023-04-27 US disclosed
US-11474045-B2 Method and device for the determination of film forming amines in a liquid FRAMATOME GMBH (DE) 2022-10-18 US disclosed
CN-110093063-B Magenta dye-based ink composition, ink set, and method for improving print quality of magenta dye-based ink composition 船井电机株式会社 2022-05-17 CN disclosed
US-20220042884-A1 DEVICES AND METHODS FOR TISSUE AND CELL STAINING (II) ESSENLIX CORPORATION (US) 2022-02-10 US disclosed
US-20210247317-A1 ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY ESSENLIX CORPORATION (US) 2021-08-12 US disclosed
CN-113227752-A Enhanced, rapid, homogeneous cell staining and assay ESSENLIX 公司 2021-08-06 CN disclosed
EP-3841368-A1 ENHANCED, RAPID, HOMOGENEOUS, CELL STAINING AND ASSAY Essenlix Corporation (US) 2021-06-30 EP disclosed
US-6600050-B2 Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes WELLA AG (DE) 2003-07-29 US disclosed
US-20030131423-A1 Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-07-17 US disclosed
EP-1317917-A1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2003-06-11 EP disclosed
US-6558433-B2 Oxidation hair dye WELLA AG (DE) 2003-05-06 US disclosed
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same Wella GmbH (DE) 2003-03-06 US disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 US disclosed
US-20020094345-A1 Pharmaceutical compositions containing epinastine and pseudoephedrine BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2002-07-18 US disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-6106579-A MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2000-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030041392-A1 Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same KRT18, SCNN1B, DDAH1 THRB 3141/4885RECQL 2960/4885TDP1 1142/4885
US-20030131423-A1 Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives KRT18, AOC1, PPOX THRB 3052/4885RECQL 2532/4885TDP1 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.