Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9306205 | 0.81 | — | — | |
| Iodide SCHEMBL9307657 | 0.78 | BCHE (0.43) | GAA | |
| Iodide SCHEMBL9307689 | 0.77 | GGPS1 (0.34) | — | |
| Iodide SCHEMBL9309183 | 0.77 | TP53 (0.35) | — | |
| Iodide SCHEMBL9307571 | 0.76 | ALDH1A1 (0.36) | — | |
| Iodide SCHEMBL9309555 | 0.75 | S1PR2 (0.43) | APLNR | |
| Iodide SCHEMBL9306187 | 0.74 | CNR2 (0.45) | — | |
| Iodide SCHEMBL9306470 | 0.74 | S1PR2 (0.42) | HPGD | |
| Iodide SCHEMBL9306247 | 0.74 | S1PR2 (0.42) | HPGD | |
| Iodide SCHEMBL9307671 | 0.73 | TP53 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |