Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9307965 | 0.84 | GGPS1 (0.37) | ALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL9306033 | 0.79 | ATM (0.46) | — | |
| Iodide SCHEMBL9309183 | 0.78 | TP53 (0.35) | — | |
| Iodide SCHEMBL9306784 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| Iodide SCHEMBL9306808 | 0.78 | THRA (0.43) | — | |
| Iodide SCHEMBL9307677 | 0.77 | — | — | |
| Iodide SCHEMBL9306047 | 0.76 | HPGD (0.38) | — | |
| Iodide SCHEMBL9309526 | 0.73 | ATM (0.52) | — | |
| Iodide SCHEMBL9308615 | 0.73 | THRA (0.45) | — | |
| Iodide SCHEMBL9306618 | 0.73 | ATM (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |