Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9305550 | 0.88 | BCHE (0.43) | — | |
| Iodide SCHEMBL9308026 | 0.87 | — | — | |
| Iodide SCHEMBL9307106 | 0.85 | MAPT (0.40) | TP53MAPT | |
| Iodide SCHEMBL9308013 | 0.83 | MEN1 (0.38) | MAPT | |
| Iodide SCHEMBL9306567 | 0.81 | LMNA (0.44) | — | |
| Iodide SCHEMBL9307790 | 0.81 | — | — | |
| Iodide SCHEMBL9306256 | 0.80 | TP53 (0.46) | TP53MAPT | |
| Iodide SCHEMBL9305907 | 0.78 | BCHE (0.46) | — | |
| Iodide SCHEMBL9307571 | 0.78 | ALDH1A1 (0.36) | — | |
| Iodide SCHEMBL9308735 | 0.77 | MAPT (0.45) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |