Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9307609 | 0.91 | POLB (0.41) | POLBTP53PLA2G4B | |
| Iodide SCHEMBL9306486 | 0.91 | POLB (0.44) | POLBTP53PLA2G4B | |
| Iodide SCHEMBL9306065 | 0.89 | TP53 (0.40) | TP53 | |
| Iodide SCHEMBL9309467 | 0.88 | THRA (0.39) | — | |
| Iodide SCHEMBL9307841 | 0.86 | POLB (0.43) | POLBTP53PLA2G4B | |
| Iodide SCHEMBL9305981 | 0.85 | — | — | |
| Iodide SCHEMBL9307369 | 0.85 | LMNA (0.41) | TP53PLA2G4B | |
| Iodide SCHEMBL9307732 | 0.85 | LMNA (0.41) | TP53PLA2G4B | |
| Iodide SCHEMBL9307222 | 0.83 | — | — | |
| Iodide SCHEMBL9306487 | 0.82 | POLB (0.41) | POLBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |