Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306609 | 0.77 | CPA1 (0.44) | ALDH1A1MAPTHDAC8LMNARECQL | |
| SCHEMBL70202 | 0.69 | ALDH1A1 (0.62) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL8902281 | 0.69 | ALDH1A1 (0.62) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL8580453 | 0.69 | ALDH1A1 (0.62) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL70201 | 0.69 | ALDH1A1 (0.62) | ALDH1A1ALOX15MAPTHDAC8KDM4E | |
| SCHEMBL20448823 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTHDAC8MEN1 | |
| SCHEMBL78873 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTHDAC8MEN1 | |
| SCHEMBL29556927 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTHDAC8MEN1 | |
| Benzene SCHEMBL28103329 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTHDAC8MEN1 | |
| SCHEMBL10590831 | 0.68 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTHDAC8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |