Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9306886 | 0.81 | CA12 (0.48) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12863045 | 0.80 | KMT2A (0.72) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL16908049 | 0.79 | KMT2A (0.77) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL9308313 | 0.76 | CYP2D6 (0.47) | CNR2 | |
| SCHEMBL9308959 | 0.74 | CXCR3 (0.48) | PDE4APDE4BPDE4CPDE4DKCNA5 | |
| SCHEMBL20393918 | 0.73 | KMT2A (0.72) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL12863387 | 0.72 | CXCR3 (0.69) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL12863586 | 0.70 | CXCR3 (0.78) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| Iodide SCHEMBL9307636 | 0.70 | CNR2 (0.46) | CA12CA1CA2CA4CA9 | |
| SCHEMBL13649423 | 0.70 | CXCR3 (0.71) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |