Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306473 | 0.88 | HPGD (0.51) | L3MBTL1 | |
| SCHEMBL9308154 | 0.80 | HSD17B10 (0.52) | PLA2G4BL3MBTL1 | |
| SCHEMBL9306665 | 0.80 | SMPD1 (0.51) | PLA2G4BSMPD1 | |
| SCHEMBL9307035 | 0.79 | MAPT (0.44) | — | |
| Iodide SCHEMBL9307611 | 0.78 | — | — | |
| SCHEMBL2189143 | 0.76 | TRPM8 (0.47) | L3MBTL1 | |
| SCHEMBL9306089 | 0.76 | CA12 (0.52) | CNR2 | |
| SCHEMBL9306979 | 0.76 | HPGD (0.56) | PLA2G4B | |
| SCHEMBL2187238 | 0.76 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL19866341 | 0.75 | EPHX2 (0.52) | PPARACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |