Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308154 | 0.81 | HSD17B10 (0.52) | HPGDHSD17B10ALDH1A1TSHRMAPK1 | |
| SCHEMBL9306473 | 0.80 | HPGD (0.51) | HPGDHSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL9306393 | 0.79 | HPGD (0.54) | HPGDHSD17B10TSHR | |
| SCHEMBL6733380 | 0.78 | HPGD (0.48) | HPGDHSD17B10ALDH1A1TSHRCYP1A2 | |
| Iodide SCHEMBL9308953 | 0.77 | PTPN1 (0.45) | PTPN1 | |
| SCHEMBL9306089 | 0.74 | CA12 (0.52) | CXCR3KCNA5ALDH1A1PDE4APDE4B | |
| SCHEMBL18422997 | 0.74 | ALDH1A1 (0.56) | CXCR3KCNA5APLNRALDH1A1TSHR | |
| SCHEMBL13572228 | 0.74 | PTGER2 (0.51) | CXCR3KCNA5 | |
| SCHEMBL9308501 | 0.73 | HPGD (0.47) | HPGDHSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL14305740 | 0.73 | CYP2D6 (0.58) | HPGDHSD17B10ALDH1A1PDE4ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529654-A1 | Benzopyran derivatives as potassium channel activators and 5-lipoxygenase inhibitors | SYNTEX (U.S.A.) INC. (US) | 1993-03-03 | — | — | EP | claimed |
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |