Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10998389 | 0.82 | CA1 (0.39) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3678596 | 0.80 | CA1 (0.57) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28628539 | 0.76 | CA12 (0.35) | CA1CA2CA7CA9CA12 | |
| SCHEMBL24631916 | 0.75 | LTA4H (0.46) | TSHRKMT2AALDH1A1MAPK1HTT | |
| SCHEMBL1880902 | 0.74 | IDO1 (0.41) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29726936 | 0.74 | IDO1 (0.41) | CA1CA2CA7CA9CA12 | |
| SCHEMBL15473266 | 0.72 | CYP1A2 (0.44) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL27207777 | 0.72 | KMT2A (0.40) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1840098 | 0.70 | ESR1 (0.31) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3956647 | 0.70 | IRAK4 (0.41) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359065-A | Reacting a bromo aromatic compound with an excess of silylating agent; forming metallized intermediate; quenching | EASTMAN KODAK COMPANY (US) | 1994-10-25 | — | — | US | disclosed |