SCHEMBL28628539

SCHEMBL28628539

C[Si](C)(C)c1ccccc1OP(Oc1ccccc1[Si](C)(C)C)Oc1ccccc1[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29797801 0.79 ESR1 (0.39) CA12CA1CA2CA4CA7
SCHEMBL10998389 0.78 CA1 (0.39) CA12CA1CA2CA4CA7
SCHEMBL13839467 0.78 CA4 (0.32) CA4
SCHEMBL13839464 0.78 CA1 (0.48) CA12CA1CA2CA4CA7
SCHEMBL13839453 0.78 TSHR (0.40)
SCHEMBL28924088 0.77 ALDH1A1 (0.31) CA12CA1CA2CA4CA7
SCHEMBL3678596 0.76 CA1 (0.57) CA12CA1CA2CA4CA7
SCHEMBL9306231 0.76 CA1 (0.38) CA12CA1CA2CA4CA7
SCHEMBL13839460 0.74 HTR1B (0.38)
SCHEMBL13839469 0.74 P2RX3 (0.37) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113413916-B Silicon-based substituted triphenyl phosphite coordination platinum catalyst, preparation method thereof and organic silicon impregnating varnish 杭州师范大学 2022-05-27 CN disclosed
CN-113413916-A Silicon-based substituted triphenyl phosphite coordination platinum catalyst, preparation method thereof and organic silicon impregnating varnish 杭州师范大学 2021-09-21 CN disclosed