Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306236 | 0.84 | KDM4E (0.43) | MEN1KMT2AMAPTPLIN1LMNA | |
| SCHEMBL10375594 | 0.84 | USP2 (0.46) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL10628854 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL10628848 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL10862684 | 0.82 | LMNA (0.46) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL10862580 | 0.81 | MAPT (0.41) | MEN1KMT2AMAPTPLIN1LMNA | |
| SCHEMBL10863359 | 0.81 | ALDH1A1 (0.47) | KMT2AMAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL4958601 | 0.79 | MAPT (0.44) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL4958597 | 0.79 | MAPT (0.44) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL7956810 | 0.78 | CYP2C19 (0.49) | MEN1KMT2AMAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |