Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305425 | 0.83 | MAPT (0.37) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9799959 | 0.71 | MAPK1 (0.34) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9306648 | 0.71 | SMN1; SMN2 (0.34) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL13475555 | 0.70 | HTT (0.51) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9306654 | 0.69 | SMN1; SMN2 (0.34) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL19122394 | 0.66 | HTT (0.49) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9306764 | 0.66 | MAPK1 (0.37) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9304640 | 0.66 | ALDH1A1 (0.35) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL29712144 | 0.64 | HTT (0.46) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9304646 | 0.63 | ALDH1A1 (0.35) | MAPTALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |