Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306407 | 0.86 | APP (0.50) | TCF4CTNNB1APPMAPTTERT | |
| SCHEMBL13996322 | 0.80 | ALDH1A1 (0.58) | TCF4CTNNB1APPMAPTTERT | |
| SCHEMBL20975977 | 0.79 | TCF4 (0.48) | TCF4CTNNB1APPMAPTTERT | |
| SCHEMBL19132656 | 0.76 | DDAH1 (0.54) | TCF4CTNNB1APPMAPTTERT | |
| SCHEMBL19132264 | 0.76 | KDM4E (0.54) | TCF4CTNNB1APPMAPTTERT | |
| SCHEMBL229608 | 0.76 | KMT2A (0.58) | MAPTKDM4EPKMALDH1A1 | |
| SCHEMBL29822916 | 0.75 | ALDH1A1 (0.37) | MAPTKDM4EPKMALDH1A1 | |
| SCHEMBL28822617 | 0.75 | ALDH1A1 (0.37) | MAPTKDM4EPKMALDH1A1 | |
| Fluoride SCHEMBL31379728 | 0.74 | KMT2A (0.56) | MAPTKDM4EPKMALDH1A1 | |
| SCHEMBL8741313 | 0.74 | KMT2A (0.56) | MAPTKDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |