SCHEMBL9306458

SCHEMBL9306458

O=C(Cl)c1ccccc1-c1ccccc1F

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
ALOX15 P16050 1/20 0.69
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
NPC1 O15118 4/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
BCHE P06276 1/20 0.42
RXFP1 Q9HBX9 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 3/20 0.40
HPGD P15428 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALB P02768 1/20 0.39
PTPN1 P18031 1/20 0.39
ERCC5 P28715 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688494 0.87 ALDH1A1 (0.58) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL993303 0.87 ALDH1A1 (0.58) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL16401432 0.84 ALDH1A1 (0.64) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL30733529 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL60101 0.82 ALDH1A1 (1.00) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL3102968 0.81 ALDH1A1 (0.55) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL269331 0.81 NPC1 (0.60) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL28382946 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15CES2CES1RAB9A
SCHEMBL1515817 0.79 CES2 (0.50) ALDH1A1ALOX15CES2CES1NPC1
SCHEMBL2113823 0.79 NPC1 (0.59) ALDH1A1ALOX15CES2CES1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6073030-A None JP disclosed
JP-H0673030-A 2-@(3754/24)2,6-DIHALOPHENYL)-4-@(3754/24)2-ALKOXY-4-ALKYL, HALO OR TRIFLUOROMETHYLPHENYL)-2-OXAZOLINES AND AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE SAME ACTIVE INGREDIENT YASHIMA CHEM IND CO LTD 1994-03-15 JP disclosed