SCHEMBL60101

SCHEMBL60101

O=C(Cl)c1ccccc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
ALOX15 P16050 1/20 1.00
CES2 O00748 3/20 0.65
CES1 P23141 3/20 0.65
GAA P10253 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
NPC1 O15118 3/20 0.50
HPGD P15428 2/20 0.50
MAPT P10636 1/20 0.50
PTPN1 P18031 1/20 0.48
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48
BCHE P06276 1/20 0.48
LMNA P02545 1/20 0.47
ALB P02768 1/20 0.45
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733529 1.00 ALDH1A1 (1.00) ALDH1A1ALOX15CES2CES1GAA
Methylene Chloride SCHEMBL27984894 0.93 ALDH1A1 (0.87) ALDH1A1ALOX15CES2CES1GAA
1,1,2,2-Tetrachloroethane SCHEMBL27984880 0.91 ALDH1A1 (0.83) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL7728989 0.88 ALDH1A1 (0.77) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL9712558 0.87 ALDH1A1 (0.76) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL27984879 0.86 ALDH1A1 (0.74) ALDH1A1ALOX15CES2CES1GAA
Anthranilic Acid SCHEMBL28306924 0.83 ALDH1A1 (0.69) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL28175067 0.83 ALDH1A1 (0.69) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL9306458 0.82 ALDH1A1 (0.69) ALDH1A1ALOX15CES2CES1GAA
SCHEMBL104744 0.81 CES2 (0.68) ALDH1A1ALOX15CES2CES1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4437 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025243250-A1 A PROCESS FOR THE PREPARATION OF 3-[5-(2-FLUOROPHENYL)-1,2,4-OXADIAZOL-3-YL]BENZOIC ACID BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2025-11-27 WO claimed
CN-119874563-A Cyclic biperoxides, synthesis method and application thereof in preparation of alkyl difunctional compounds 西安交通大学 2025-04-25 CN claimed
CN-118571634-B Preparation process of nanocrystalline iron core containing flexible epoxy resin for high-frequency transformer 曼特(广州)磁性器件有限公司 2025-04-11 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-222658612-U Hydrolysis equipment is used in fluorobenzoyl chloride production 江苏万隆化学有限公司 2025-03-25 CN claimed
CN-117467492-B Refrigerator oil composition for hydrofluorocarbon and preparation method thereof 安徽宜度科技有限公司 2025-03-18 CN claimed
US-20240287008-A1 METHOD FOR THE SYNTHESIS OF 3-R-1,4,2-DIOXAZOL-5-ONES PANASONIC HOLDINGS CORPORATION (JP) 2024-08-29 US claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
EP-1572751-A4 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2006-07-19 EP claimed
EP-1572751-A2 POLYMERIZATION PROCESSES ExxonMobil Chemical Patents Inc. (US) 2005-09-14 EP claimed
CN-1164564-C Process for preparing high purity 2-amino-5-chloro-2'-diphenyl ketone 岑 坚 2004-09-01 CN claimed
WO-2004067577-A2 POLYMERIZATION PROCESSES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-08-12 WO claimed
CN-1326924-A Process for preparing high purity 2-amino-5-chloro-2'-diphenyl ketone CEN JIAN (CN) 2001-12-19 CN claimed
EP-0653414-B1 Process for preparing alkyl esters of fluorbenzoic acid by reaction of a fluor-benzoylchlorides with an alcohol in the presence of an alkalimetal alcoholate HOECHST AG (DE) 1997-09-17 EP claimed
US-5446190-A Process for the preparation of alkyl fluorobenzoates in high purity and high yield HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-29 US claimed
EP-0653414-A1 Process for preparing alkyl esters of fluorbenzoic acid by reaction of a fluor-benzoylchlorides with an alkohol in the presence of an alkalimetal alcoholate HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-17 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed