Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017265 | 0.81 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 | |
| SCHEMBL12648774 | 0.79 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1MAP3K14MCL1 | |
| SCHEMBL29936962 | 0.79 | MAPT (0.48) | PTGS2PTGS1ALDH1A1MAP3K14MCL1 | |
| SCHEMBL3084322 | 0.78 | ALDH1A1 (0.55) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 | |
| SCHEMBL29702110 | 0.78 | ALDH1A1 (0.55) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 | |
| SCHEMBL17359234 | 0.78 | NISCH (0.42) | PTGS2PTGS1 | |
| SCHEMBL10304835 | 0.76 | PTGS2 (0.43) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 | |
| SCHEMBL6724157 | 0.75 | PTGS2 (0.68) | PTGS2PTGS1CA9 | |
| Lithium SCHEMBL30110458 | 0.75 | ALDH1A1 (0.60) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 | |
| SCHEMBL5390940 | 0.75 | ALDH1A1 (0.52) | PTGS2PTGS1ALDH1A1MCL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6072950-A | — | — | None | — | — | JP | disclosed |
| JP-H0672950-A | FLUORO-P-TERPHENYL DERIVATIVE AND ITS PRODUCTION | ASAHI GLASS CO LTD | 1994-03-15 | — | — | JP | disclosed |