Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936713 | 0.81 | HSD17B1 (0.41) | MAPTALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL25332785 | 0.80 | SLC6A3 (0.50) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29936760 | 0.80 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL9306464 | 0.79 | PTGS2 (0.47) | MAPTALDH1A1TSHRCYP3A4PTGS2 | |
| SCHEMBL29936733 | 0.79 | CNR2 (0.54) | MAPTLMNAALDH1A1POLBKMT2A | |
| SCHEMBL29936878 | 0.78 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL505248 | 0.77 | LMNA (0.57) | LMNAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL505633 | 0.75 | TSHR (0.46) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL505395 | 0.75 | ALDH1A1 (0.53) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29936785 | 0.75 | L3MBTL1 (0.49) | MAPTLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010600-B | Method for synthesizing polyfluoroaryl carboxylic acid compound based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-115010600-A | Method for synthesizing polyfluoroaryl carboxylic acid compounds based on aryl fluorocarbon bond carboxylation reaction | 四川大学 | 2022-09-06 | — | — | CN | disclosed |