Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 6/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986588 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL10871798 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL6266857 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL4598873 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL8769895 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL3976207 | 0.91 | PTPN11 (0.60) | THRATHRBPTPN11ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8419150 | 0.90 | PTPN11 (0.58) | THRATHRBPTPN11ALDH1A1HPGD | |
| SCHEMBL3975412 | 0.87 | THRA (0.56) | THRATHRBPTPN11SMPD1KDM4E | |
| SCHEMBL8419148 | 0.87 | THRA (0.56) | THRATHRBPTPN11SMPD1KDM4E | |
| SCHEMBL3973609 | 0.85 | MKNK1 (0.47) | LMNAKMT2AKDM4EPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5320776-A | Antiferroelectric liquid crystal compound | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1994-06-14 | — | — | US | disclosed |