Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266857 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL10871798 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL3976207 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8986588 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8769895 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8419150 | 0.99 | PTPN11 (0.58) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL3975412 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8419148 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL9306503 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| Terephthalic Acid SCHEMBL10581511 | 0.89 | RXRA (0.62) | PTPN11THRATHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907347-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | Arcadia Pharmaceuticals Inc. (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009083-A2 | COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2007-01-18 | — | — | WO | disclosed |
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |