Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266857 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL10871798 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8986588 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8769895 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL4598873 | 1.00 | PTPN11 (0.60) | PTPN11THRATHRBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8419150 | 0.99 | PTPN11 (0.58) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL3975412 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL8419148 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| SCHEMBL9306503 | 0.91 | THRA (0.56) | PTPN11THRATHRBALDH1A1HPGD | |
| Terephthalic Acid SCHEMBL10581511 | 0.89 | RXRA (0.62) | PTPN11THRATHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057173-A1 | AMIDES AS SPHINGOMYELINE INHIBITORS | Novartis AG (CH) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008022771-A1 | AMIDES AS SPHINGOMYELINE INHIBITORS | NOVARTIS AG (CH) | 2008-02-28 | — | — | WO | disclosed |
| US-6139946-A | Magnetic recording media incorporating a quaternary ammonium functional binder and magnetic pigment surface treated with compound having acidic and electron withdrawing functionalities | IMATION CORP. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0789579-A4 | AZA CYCLOHEXAPEPTIDE COMPOUNDS | MERCK & CO INC (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0789579-A1 | AZA CYCLOHEXAPEPTIDE COMPOUNDS | Merck & Co., Inc. (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0571278-B1 | Antiferroelectric liquid crystal compound and process for producing the same | SHOWA SHELL SEKIYU (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5344586-A | Antiferroelectric liquid crystal compound and process for producing the same | SHOWA SHEEL SEKIYU KABUSHIKI KAISHA (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0571278-A1 | Antiferroelectric liquid crystal compound and process for producing the same | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0341713-A2 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0333760-A1 | CYANO-ALICYCLIC ESTERS AND LIQUID CRYSTAL COMPOSITIONS. | SECR DEFENCE BRIT (GB) | 1989-09-27 | — | — | EP | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| WO-1988004290-A1 | CYANO-ALICYCLIC ESTERS IN LIQUID CRYSTAL COMPOSITIONS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1988-06-16 | — | — | WO | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |